Prabhat Kumar Singh*, Saswata Goswami, A. S. Vidyarthi


Our reliance on petroleum derived plastic materials and their uncontrolled utilization are the major cause of waste accumulation on landfill and release of greenhouse gases. Modern biological techniques are intended in order to the development of eco-friendly and biodegradable polymeric materials that exert negligible hazardous effect on our environment. A biologically-synthesized plastic material namely polyhydroxyalkanoate (PHA), has been attracting significant interest of scientists and researchers because of its gorgeous physical and mechanical properties similar to conventional plastics produced from petroleum products. Besides of conventional plastics, PHA is synthesized from renewable resources and is degraded by bacteria in aerobic condition into CO2 and H2O when disposed in waste stream. The selection of proper bacterial strains, cheap carbon sources, proficient fermentation process and recovery techniques are important factors that should be taken into deliberation for the commercial production of PHA. This review mainly focuses on economical strategies to diminish the production costs of PHA as well as its applications in different fields.


PHA; renewable resources; biosynthesis of PHA; bacterial strain; fermentation process; downstream processing

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